COVID-19 Exacerbates Neurovascular Uncoupling and Contributes to Endothelial Dysfunction in Patients with Mild Cognitive Impairment

COVID-19 Exacerbates Neurovascular Uncoupling and Contributes to Endothelial Dysfunction in Patients with Mild Cognitive Impairment

Mild cognitive impairment (MCI) affects nearly 20% of older adults worldwide, with no targetable interventions for prevention. COVID-19 adversely affects cognition, with >70% of older adults with Long COVID presenting with cognitive complaints. Neurovascular coupling (NVC), an essential mechanism...

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Main Authors: Cameron D. Owens, Camila B. Pinto, Zsofia Szarvas, Mihaly Muranyi, Ana Clara da C. Pinaffi-Langley, Anna Peterfi, Peter Mukli, Sam Detwiler, Lauren Olay, Zalan Kaposzta, Kenneth Smith, Angelia C. Kirkpatrick, Faddi Saleh Velez, Stefano Tarantini, Anna Csiszar, Zoltan I. Ungvari, Calin I. Prodan, Andriy Yabluchanskiy
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Biomolecules
Subjects:
mild cognitive impairment
neurovascular coupling
COVID-19
endothelial function
flow-mediated dilation
Online Access:https://www.mdpi.com/2218-273X/14/12/1621
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