Naturally acquired IgG responses to Plasmodium falciparum do not target the conserved termini of the malaria vaccine candidate Merozoite Surface Protein 2

Naturally acquired IgG responses to Plasmodium falciparum do not target the conserved termini of the malaria vaccine candidate Merozoite Surface Protein 2

IntroductionMalaria remains a significant burden, and a fully protective vaccine against Plasmodium falciparum is critical for reducing morbidity and mortality. Antibody responses against the blood-stage antigen Merozoite Surface Protein 2 (MSP2) are associated with protection from P. falciparum mal...

Full description

Saved in:
Bibliographic Details
Main Authors: Julia Zerebinski, Lucille Margerie, Nan Sophia Han, Maximilian Moll, Matias Ritvos, Peter Jahnmatz, Niklas Ahlborg, Billy Ngasala, Ingegerd Rooth, Ronald Sjöberg, Christopher Sundling, Victor Yman, Anna Färnert, David Fernando Plaza
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Immunology
Subjects:
malaria vaccine
merozoite
polymorphic antigens
immune evasion
structural heterogeneity
antibody response
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1501700/full
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2024.1501700/full

Similar Items