Generation of an inducible dCas9-SAM human PSC line for endogenous gene activation
The CRISPR/Cas9 system has transformed genome editing by enabling precise modifications for diverse applications. Recent advancements, including base editing and prime editing, have expanded its utility beyond conventional gene knock-out and knock-in strategies. Additionally, several catalytically d...
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          | Main Authors: | Paolo Petazzi, Francisco Gutierrez-Agüera, Heleia Roca-Ho, Julio Castaño, Clara Bueno, Niuska Alvarez, Lesley M. Forrester, Ana Sevilla, Antonella Fidanza, Pablo Menendez | 
|---|---|
| Format: | Article | 
| Language: | English | 
| Published: | Frontiers Media S.A.
    
        2024-11-01 | 
| Series: | Frontiers in Cell and Developmental Biology | 
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fcell.2024.1484955/full | 
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