Overcoming β-Cell Dysfunction in Type 2 Diabetes Mellitus: CD36 Inhibition and Antioxidant System

Type 2 diabetes mellitus (T2DM) is marked by chronic hyperglycemia, gradually worsening β-cell failure, and insulin resistance. Glucotoxicity and oxidative stress cause β-cell failure by increasing reactive oxygen species (ROS) production, impairing insulin secretion, and disrupting transcription fa...

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Bibliographic Details
Main Authors: Il Rae Park, Yong Geun Chung, Kyu Chang Won
Format: Article
Language:English
Published: Korean Diabetes Association 2025-01-01
Series:Diabetes & Metabolism Journal
Subjects:
Online Access:http://e-dmj.org/upload/pdf/dmj-2024-0796.pdf
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