Overcoming β-Cell Dysfunction in Type 2 Diabetes Mellitus: CD36 Inhibition and Antioxidant System
Type 2 diabetes mellitus (T2DM) is marked by chronic hyperglycemia, gradually worsening β-cell failure, and insulin resistance. Glucotoxicity and oxidative stress cause β-cell failure by increasing reactive oxygen species (ROS) production, impairing insulin secretion, and disrupting transcription fa...
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Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Korean Diabetes Association
2025-01-01
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Series: | Diabetes & Metabolism Journal |
Subjects: | |
Online Access: | http://e-dmj.org/upload/pdf/dmj-2024-0796.pdf |
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