PPP6R3-mediated dephosphorylation regulates mRNA translation during spermatogonial differentiation

Abstract Protein dephosphorylation mediated by phosphatases regulates spermatogenesis. However, which proteins are dephosphorylated and how they regulate spermatogenesis are largely unknown. Here, we show that germline-specific deletion of protein phosphatase 6 regulatory subunit 3 (PPP6R3), which d...

Full description

Saved in:
Bibliographic Details
Main Authors: Qian Fang, Biyun Liu, Jie Cen, Tongtong Li, Shuhui Ji, Wenqing Li, Gang Lu, Zi-Jiang Chen, Xin Wang, Jianqiang Bao, Hongbin Liu
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-08539-1
Tags: Add Tag
No Tags, Be the first to tag this record!