Immunogenicity Assessment of a 14-Valent Human Papillomavirus Vaccine Candidate in Mice

Immunogenicity Assessment of a 14-Valent Human Papillomavirus Vaccine Candidate in Mice

Background: Cervical cancer ranks as the fourth most common cancer affecting women globally, with HPV as the primary etiology agent. Prophylactic HPV vaccines have substantially reduced the incidence of cervical cancer. Methods: This study assessed the immunogenicity of SCT1000, a 14-valent recombin...

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Main Authors: Lei Bei, Shuman Gao, Dandan Zhao, Yajuan Kou, Siyu Liang, Yurong Wu, Xiao Zhang, Dan Meng, Jianbo Lu, Chunxia Luo, Xuefeng Li, Yang Wang, Hongbin Qiu, Liangzhi Xie
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Vaccines
Subjects:
HPV
vaccine
pseudovirion-based neutralization assay (PBNA)
total IgG Luminex immunoassay (total IgG LIA)
immunogenicity
correlation analysis
Online Access:https://www.mdpi.com/2076-393X/12/11/1262
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https://www.mdpi.com/2076-393X/12/11/1262

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