Inducible Fgf13 ablation alleviates cardiac fibrosis via regulation of microtubule stability

Inducible Fgf13 ablation alleviates cardiac fibrosis via regulation of microtubule stability

Fibroblast growth factor (FGF) isoform 13, a distinct type of FGF, boasts significant potential for therapeutic intervention in cardiovascular dysfunctions. However, its impact on regulating fibrosis remains unexplored. This study aims to elucidate the role and mechanism of FGF13 on cardiac fibrosis...

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Main Authors: Wang Cong, Wang Xiangchong, Zhang Yiyi, Mi Yuan, Han Yanxue, Zhi Yaxin, Zhao Ran, Cui Nanqi, Ma Qianli, Zhang Huaxing, Xue Dazhong, Qiao Ruoyang, Han Jiabing, Yu Yulou, Li Jiaxuan, Shaiea Mohammed, Liu Demin, Gu Guoqiang, Wang Chuan
Format: Article
Language:English
Published: China Science Publishing & Media Ltd. 2024-05-01
Series:Acta Biochimica et Biophysica Sinica
Subjects:
FGF13
cardiac fibrosis
fibroblasts
microtubule
ROCK
Online Access:https://www.sciengine.com/doi/10.3724/abbs.2024075
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https://www.sciengine.com/doi/10.3724/abbs.2024075

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