Exploring CD169<sup>+</sup> Macrophages as Key Targets for Vaccination and Therapeutic Interventions

CD169 is a sialic acid-binding immunoglobulin-like lectin (Siglec-1, sialoadhesin) that is expressed by subsets of tissue-resident macrophages and circulating monocytes. This receptor interacts with α2,3-linked Neu5Ac on glycoproteins as well as glycolipids present on the surface of immune cells and...

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Bibliographic Details
Main Authors: Rianne G. Bouma, Aru Z. Wang, Joke M. M. den Haan
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Vaccines
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Online Access:https://www.mdpi.com/2076-393X/13/3/330
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