SOCS3 and IL-6 mRNA levels in PBMC enhance the early prediction for patients with acute-on-chronic hepatitis B liver failure receiving glucocorticoid therapy

SOCS3 and IL-6 mRNA levels in PBMC enhance the early prediction for patients with acute-on-chronic hepatitis B liver failure receiving glucocorticoid therapy

IntroductionEarly prediction is essential in hepatitis B virus-related acute-on-chronic liver failure (ACHBLF) patients receiving glucocorticoid therapy. Interleukin (IL)-6 is the main factor of cytokine storm that occurs in ACHBLF. IL-6 and suppressors of cytokine signaling 3 (SOCS3) may be associa...

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Bibliographic Details
Main Authors: Ji-Hui Li, Jing Wang, Han-Xu Zhu, Feng Zhang, Yu-Na Tang, Jing-Wei Wang, Yu-Chen Fan, Hui-Hui Liu, Kai Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
acute-on-chronic hepatitis B liver failure
glucocorticoid
prognosis prediction
SOCS3
IL-6
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2025.1571443/full
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