Association of ABCB1 G2677T polymorphism with atorvastatin lipid efficacy and extended prognosis in patients with cerebral ischemic stroke

Association of ABCB1 G2677T polymorphism with atorvastatin lipid efficacy and extended prognosis in patients with cerebral ischemic stroke

Abstract To investigate the association between ABCB1 (2677T > G) (rs2032582) polymorphism and lipid-lowering efficacy of atorvastatin with long-term prognosis in patients with cerebral ischemic stroke (CIS). A prospective cohort of 127 CIS patients admitted to Xuchang Central Hospital from Janua...

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Bibliographic Details
Main Authors: Yingna Tian, Bingxin Xu, Shuling Guo, Qinghua Li, Haigang Zhao, Yan Zhao, Hanjing Wei, Wei Liu, Pengfei Gao, Wei Li, Xianjun Zhang
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
ABCB1 (2677T > G)
Genetic polymorphism
Cerebral ischemic stroke
Atorvastatin
Lipid-lowering efficacy
Long-term prognostic outcomes
Online Access:https://doi.org/10.1038/s41598-025-15434-6
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https://doi.org/10.1038/s41598-025-15434-6

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