Deciphering distinct pathogenic mechanisms of ankylosing spondylitis and systemic sclerosis via shared biomarkers ZSWIM6 and CCL3L3: Insights from an integrative bioinformatics approach

Deciphering distinct pathogenic mechanisms of ankylosing spondylitis and systemic sclerosis via shared biomarkers ZSWIM6 and CCL3L3: Insights from an integrative bioinformatics approach

Ankylosing Spondylitis (AS) and Systemic Sclerosis (SSc) are both autoimmune diseases, albeit with distinct anatomical targets. AS primarily affects the spine and sacroiliac joints, triggering inflammation and eventual fusion of the vertebrae. SSc predominantly impacts the skin and connective tissue...

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Main Authors: Liangyu Huang, Jiarui Chen, Renbang Yang, Jianjun Shi, Chenxing Zhou, Tianyou Chen, Sitan Feng, Chengqian Huang, Jieping Huang, Jiang Xue, Zhongxian Zhou, Jichong Zhu, Shaofeng Wu, Xinli Zhan, Chong Liu
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Autoimmunity
Subjects:
AS
SSc
immune gene
ZSWIM6
CCL3L3
Online Access:https://www.tandfonline.com/doi/10.1080/08916934.2024.2445557
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https://www.tandfonline.com/doi/10.1080/08916934.2024.2445557

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