Characterizing microbial communities and their correlation with genetic mutations in early-stage lung adenocarcinoma: implications for disease progression and therapeutic targets

Characterizing microbial communities and their correlation with genetic mutations in early-stage lung adenocarcinoma: implications for disease progression and therapeutic targets

BackgroundLung adenocarcinoma (LUAD), the most prevalent form of lung cancer. The transition from adenocarcinoma in situ (AIS), and minimally invasive adenocarcinoma (MIA) to invasive adenocarcinoma (IAC) is not fully understood. Intratumoral microbiota may play a role in LUAD progression, but compr...

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Bibliographic Details
Main Authors: Hao-Shuai Yang, Jin Zhang, Hong-Xiang Feng, Fei Qi, Fan-Jia Kong, Wei-Jie Zhu, Chao-Yang Liang, Zhen-Rong Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Oncology
Subjects:
lung adenocarcinoma
tumor microbiome
PTPRZ1
next-generation sequencing
therapeutic targets
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1498524/full
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