Evaluating the amoeba thioredoxin reductase selenoprotein as potential drug target for treatment of Acanthamoeba infections

The genus Acanthamoeba comprises facultative pathogens, causing Acanthamoeba keratitis (AK) and granulomatous amoebic encephalitis (GAE). In both diseases, treatment options are limited, and drug development is challenging. This study aimed to investigate the role of the large thioredoxin reductase...

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Bibliographic Details
Main Authors: Alvie Loufouma-Mbouaka, Attila Andor, David Leitsch, Jorge Pérez-Serrano, Elias S.J. Arnér, Julia Walochnik, Tania Martín-Pérez
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:International Journal for Parasitology: Drugs and Drug Resistance
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Online Access:http://www.sciencedirect.com/science/article/pii/S2211320724000459
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