Metabolic engineering of Yarrowia lipolytica for the production and secretion of the saffron ingredient crocetin

Metabolic engineering of Yarrowia lipolytica for the production and secretion of the saffron ingredient crocetin

Abstract Background Crocetin is a multifunctional apocarotenoid natural product derived from saffron, holding significant promises for protection against various diseases and other nutritional applications. Historically, crocetin has been extracted from saffron stigmas, but this method is hindered b...

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Bibliographic Details
Main Authors: Tingan Zhou, Young-Kyoung Park, Jing Fu, Piotr Hapeta, Cinzia Klemm, Rodrigo Ledesma-Amaro
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Biotechnology for Biofuels and Bioproducts
Subjects:
Crocetin
Zeaxanthin
β-Carotene
Yarrowia lipolytica
Secretory biosynthesis
Metabolic engineering
Online Access:https://doi.org/10.1186/s13068-024-02598-y
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