Targeting KIFC1 Promotes Senescence in Soft Tissue Sarcoma via FXR1‐Dependent Regulation of MAD2L1 mRNA Stability

Abstract Patients diagnosed with soft tissue sarcoma (STS) often present at intermediate to advanced stages, with inherently limited therapeutic options available. There is an urgent need to identify novel therapeutic targets. In this study, by screening STS data from the Cancer Genome Atlas (TCGA)...

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Bibliographic Details
Main Authors: Xiu‐Xia Lu, Yi Que, Jing Yang, Li‐Yuan Le, Qi‐Yan Cai, Bu‐Shu Xu, Dong‐Chun Hong, Yao Liang, Xing Zhang
Format: Article
Language:English
Published: Wiley 2024-11-01
Series:Advanced Science
Subjects:
Online Access:https://doi.org/10.1002/advs.202405611
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