Addressing the Evolution of Cardenolide Formation in Iridoid-Synthesizing Plants: Site-Directed Mutagenesis of PRISEs (Progesterone-5β-Reductase/Iridoid Synthase-like Enzymes) of Plantago Species

Addressing the Evolution of Cardenolide Formation in Iridoid-Synthesizing Plants: Site-Directed Mutagenesis of PRISEs (Progesterone-5β-Reductase/Iridoid Synthase-like Enzymes) of Plantago Species

Enzymes capable of processing a variety of compounds enable plants to adapt to diverse environmental conditions. PRISEs (progesterone-5β-reductase/iridoid synthase-like enzymes), examples of such substrate-promiscuous enzymes, are involved in iridoid and cardenolide pathways and demonstrate notable...

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Bibliographic Details
Main Authors: Maja Dorfner, Jan Klein, Katharina Senkleiter, Harald Lanig, Wolfgang Kreis, Jennifer Munkert
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Molecules
Subjects:
<i>Plantago lanceolata</i>
<i>Plantago media</i>
iridoid biosynthesis
progesterone
PRISEs
cardenolides
Online Access:https://www.mdpi.com/1420-3049/29/23/5788
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