Evolutionary history of calcium-sensing receptors unveils hyper/hypocalcemia-causing mutations.

Despite advancements in understanding the structure and functions of the Calcium Sensing Receptor (CaSR), gaps persist in our knowledge of the specific functions of its residues. In this study, we used phylogeny-based techniques to identify functionally equivalent orthologs of CaSR, predict residue...

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Bibliographic Details
Main Authors: Aylin Bircan, Nurdan Kuru, Onur Dereli, Berkay Selçuk, Ogün Adebali
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-11-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1012591
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