A ROLE FOR INTERLEUKIN 8 IN DIRECT REGULATION OF T CELL FUNCTIONAL ACTIVITY

A ROLE FOR INTERLEUKIN 8 IN DIRECT REGULATION OF T CELL FUNCTIONAL ACTIVITY

CD3+T lymphocytes were isolated from normal donors by positive magnetic separation. Activation of the T cells with particles conjugated with antibodies to CD3, СD28 and СD2 molecules led to substantial increase in T cell production of interleukin-8 (IL-8). An interleukin-8 receptor (CXCR1, CD181) wa...

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Bibliographic Details
Main Authors: M. E. Meniailo, V. V. Malashchenko, V. A. Shmarov, N. D. Gasatova, O. B. Melashchenko, A. G. Goncharov, G. V. Seledtsova, V. I. Seledtsov
Format: Article
Language:Russian
Published: St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists 2017-10-01
Series:Медицинская иммунология
Subjects:
interleukin-8
t lymphocytes
interleukin 8 receptor
activation of lymphocytes
cytokines
functional activity
Online Access:https://www.mimmun.ru/mimmun/article/view/1352
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