The Correlation between Computed Tomography Severity Grade and Pulmonary Function in Interstitial Lung Disease
Objective: To assess whether there is a correlation between CT scan severity score and pulmonary function in Interstitial Lung Disease, and provide a more reliable basis for clinical diagnosis and treatment. Materials and Methods: Sixty patients with clinical diagnosis of Interstitial Lung Disease (...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Editorial Office of Computerized Tomography Theory and Application
2025-07-01
|
| Series: | CT Lilun yu yingyong yanjiu |
| Subjects: | |
| Online Access: | https://www.cttacn.org.cn/cn/article/doi/10.15953/j.ctta.2024.305 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849321353423880192 |
|---|---|
| author | Hui GAO Yongbin LIU Min XIAO Jing ZHANG Qin LIU |
| author_facet | Hui GAO Yongbin LIU Min XIAO Jing ZHANG Qin LIU |
| author_sort | Hui GAO |
| collection | DOAJ |
| description | Objective: To assess whether there is a correlation between CT scan severity score and pulmonary function in Interstitial Lung Disease, and provide a more reliable basis for clinical diagnosis and treatment. Materials and Methods: Sixty patients with clinical diagnosis of Interstitial Lung Disease (ILD) were collected, and chest CT and pulmonary function tests were performed at the same time. Here DLCO% and FEV1% were used as the pulmonary function indexes. The severity of the patients was assessed by CT scores as mild (range, 1~10), moderate (range 11~20), and severe (range 21~30). Correlation analysis was carried out between CT score and pulmonary function index, and the lung function parameters of patients at three grades were compared between groups and pairwise among the means. Results: As per the CT severity classification, there were 13 mild cases, 31 moderate cases, and 16 severe cases. CT score was negatively correlated with DLCO% and FEV1%. R value was −0.814 and −0.797, respectively; The comparison of the mean value of DLCO% and FEV1% among the three groups and the pairings of the mean value of DLCO% and FEV1% were statistically significant. Conclusion: There was good correlation between CT score of ILD and the pulmonary function index. The pulmonary function index of patients with different CT severity grading was statistically significant, which can provide a new basis for the clinical evaluation and diagnosis of the disease. |
| format | Article |
| id | doaj-art-a24cf222f99b4ad6ab5116f4c957ebbb |
| institution | Kabale University |
| issn | 1004-4140 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Editorial Office of Computerized Tomography Theory and Application |
| record_format | Article |
| series | CT Lilun yu yingyong yanjiu |
| spelling | doaj-art-a24cf222f99b4ad6ab5116f4c957ebbb2025-08-20T03:49:46ZengEditorial Office of Computerized Tomography Theory and ApplicationCT Lilun yu yingyong yanjiu1004-41402025-07-0134459860310.15953/j.ctta.2024.3052024-305The Correlation between Computed Tomography Severity Grade and Pulmonary Function in Interstitial Lung DiseaseHui GAO0Yongbin LIU1Min XIAO2Jing ZHANG3Qin LIU4Department of Radiology, Shenzhen Nanshan People’s Hospital, Shenzhen 518052, ChinaDepartment of Radiology, Shenzhen Nanshan People’s Hospital, Shenzhen 518052, ChinaDepartment of Radiology, Shenzhen Nanshan People’s Hospital, Shenzhen 518052, ChinaDepartment of Radiology, Shenzhen Nanshan People’s Hospital, Shenzhen 518052, ChinaDepartment of Radiology, First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510120, ChinaObjective: To assess whether there is a correlation between CT scan severity score and pulmonary function in Interstitial Lung Disease, and provide a more reliable basis for clinical diagnosis and treatment. Materials and Methods: Sixty patients with clinical diagnosis of Interstitial Lung Disease (ILD) were collected, and chest CT and pulmonary function tests were performed at the same time. Here DLCO% and FEV1% were used as the pulmonary function indexes. The severity of the patients was assessed by CT scores as mild (range, 1~10), moderate (range 11~20), and severe (range 21~30). Correlation analysis was carried out between CT score and pulmonary function index, and the lung function parameters of patients at three grades were compared between groups and pairwise among the means. Results: As per the CT severity classification, there were 13 mild cases, 31 moderate cases, and 16 severe cases. CT score was negatively correlated with DLCO% and FEV1%. R value was −0.814 and −0.797, respectively; The comparison of the mean value of DLCO% and FEV1% among the three groups and the pairings of the mean value of DLCO% and FEV1% were statistically significant. Conclusion: There was good correlation between CT score of ILD and the pulmonary function index. The pulmonary function index of patients with different CT severity grading was statistically significant, which can provide a new basis for the clinical evaluation and diagnosis of the disease.https://www.cttacn.org.cn/cn/article/doi/10.15953/j.ctta.2024.305lung diseaseinterstitialctseverity gradepulmonary function |
| spellingShingle | Hui GAO Yongbin LIU Min XIAO Jing ZHANG Qin LIU The Correlation between Computed Tomography Severity Grade and Pulmonary Function in Interstitial Lung Disease CT Lilun yu yingyong yanjiu lung disease interstitial ct severity grade pulmonary function |
| title | The Correlation between Computed Tomography Severity Grade and Pulmonary Function in Interstitial Lung Disease |
| title_full | The Correlation between Computed Tomography Severity Grade and Pulmonary Function in Interstitial Lung Disease |
| title_fullStr | The Correlation between Computed Tomography Severity Grade and Pulmonary Function in Interstitial Lung Disease |
| title_full_unstemmed | The Correlation between Computed Tomography Severity Grade and Pulmonary Function in Interstitial Lung Disease |
| title_short | The Correlation between Computed Tomography Severity Grade and Pulmonary Function in Interstitial Lung Disease |
| title_sort | correlation between computed tomography severity grade and pulmonary function in interstitial lung disease |
| topic | lung disease interstitial ct severity grade pulmonary function |
| url | https://www.cttacn.org.cn/cn/article/doi/10.15953/j.ctta.2024.305 |
| work_keys_str_mv | AT huigao thecorrelationbetweencomputedtomographyseveritygradeandpulmonaryfunctionininterstitiallungdisease AT yongbinliu thecorrelationbetweencomputedtomographyseveritygradeandpulmonaryfunctionininterstitiallungdisease AT minxiao thecorrelationbetweencomputedtomographyseveritygradeandpulmonaryfunctionininterstitiallungdisease AT jingzhang thecorrelationbetweencomputedtomographyseveritygradeandpulmonaryfunctionininterstitiallungdisease AT qinliu thecorrelationbetweencomputedtomographyseveritygradeandpulmonaryfunctionininterstitiallungdisease AT huigao correlationbetweencomputedtomographyseveritygradeandpulmonaryfunctionininterstitiallungdisease AT yongbinliu correlationbetweencomputedtomographyseveritygradeandpulmonaryfunctionininterstitiallungdisease AT minxiao correlationbetweencomputedtomographyseveritygradeandpulmonaryfunctionininterstitiallungdisease AT jingzhang correlationbetweencomputedtomographyseveritygradeandpulmonaryfunctionininterstitiallungdisease AT qinliu correlationbetweencomputedtomographyseveritygradeandpulmonaryfunctionininterstitiallungdisease |