NR2F6 regulates stem cell hematopoiesis and myelopoiesis in mice

NR2F6 regulates stem cell hematopoiesis and myelopoiesis in mice

Nuclear receptors regulate hematopoietic stem cells (HSCs) and peripheral immune cells in mice and humans. The nuclear orphan receptor NR2F6 (EAR-2) has been shown to control murine hematopoiesis. Still, detailed analysis of the distinct stem cell, myeloid, and lymphoid progenitors in the bone marro...

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Bibliographic Details
Main Authors: Johannes Woelk, Hamsa Narasimhan, Christa Pfeifhofer-Obermair, Barbara U. Schraml, Natascha Hermann-Kleiter
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Immunology
Subjects:
nuclear receptor NR2F6
bone marrow
hematopoiesis
HSC
GMP
MDP
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1404805/full
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