Expanding the Donor Pool

Given the aging population and despite advances in heart failure therapies, the number of patients with advanced heart failure in need of heart transplantation continues to increase, and the longstanding mismatch between organ demand and organ supply persists. In an effort to address this mismatch a...

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Main Authors: Saleem Toro, Kelly H. Schlendorf
Format: Article
Language:English
Published: Houston Methodist DeBakey Heart & Vascular Center 2025-05-01
Series:Methodist DeBakey Cardiovascular Journal
Subjects:
Online Access:https://account.journal.houstonmethodist.org/index.php/up-j-mdbcj/article/view/1577
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author Saleem Toro
Kelly H. Schlendorf
author_facet Saleem Toro
Kelly H. Schlendorf
author_sort Saleem Toro
collection DOAJ
description Given the aging population and despite advances in heart failure therapies, the number of patients with advanced heart failure in need of heart transplantation continues to increase, and the longstanding mismatch between organ demand and organ supply persists. In an effort to address this mismatch and expand the donor pool, a number of strategies are being pursued. This article reviews several of those strategies, including transplantation from hepatitis C virus-infected donors, transplantation from donors after circulatory death, the role of organ preservation technologies in facilitating transplantation of hearts that might otherwise be discarded, and the impact of public education and national donation policies.
format Article
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institution Kabale University
issn 1947-6108
language English
publishDate 2025-05-01
publisher Houston Methodist DeBakey Heart & Vascular Center
record_format Article
series Methodist DeBakey Cardiovascular Journal
spelling doaj-art-a1ff3b208f8045c19d9b08adfe6bf29d2025-08-20T03:47:06ZengHouston Methodist DeBakey Heart & Vascular CenterMethodist DeBakey Cardiovascular Journal1947-61082025-05-01213333910.14797/mdcvj.15771555Expanding the Donor PoolSaleem Toro0https://orcid.org/0000-0002-3654-7118Kelly H. Schlendorf1https://orcid.org/0000-0002-8811-1957Vanderbilt Heart and Vascular Institute, Nashville, TennesseeVanderbilt Heart and Vascular Institute, Nashville, TennesseeGiven the aging population and despite advances in heart failure therapies, the number of patients with advanced heart failure in need of heart transplantation continues to increase, and the longstanding mismatch between organ demand and organ supply persists. In an effort to address this mismatch and expand the donor pool, a number of strategies are being pursued. This article reviews several of those strategies, including transplantation from hepatitis C virus-infected donors, transplantation from donors after circulatory death, the role of organ preservation technologies in facilitating transplantation of hearts that might otherwise be discarded, and the impact of public education and national donation policies.https://account.journal.houstonmethodist.org/index.php/up-j-mdbcj/article/view/1577heart transplantationhepatitis cdcdnrporgan donororgan preservationtransplant policy
spellingShingle Saleem Toro
Kelly H. Schlendorf
Expanding the Donor Pool
Methodist DeBakey Cardiovascular Journal
heart transplantation
hepatitis c
dcd
nrp
organ donor
organ preservation
transplant policy
title Expanding the Donor Pool
title_full Expanding the Donor Pool
title_fullStr Expanding the Donor Pool
title_full_unstemmed Expanding the Donor Pool
title_short Expanding the Donor Pool
title_sort expanding the donor pool
topic heart transplantation
hepatitis c
dcd
nrp
organ donor
organ preservation
transplant policy
url https://account.journal.houstonmethodist.org/index.php/up-j-mdbcj/article/view/1577
work_keys_str_mv AT saleemtoro expandingthedonorpool
AT kellyhschlendorf expandingthedonorpool