PHOTOTHERAPY AND PHOTODYNAMIC THERAPY IN THE TREATMENT OF EXTRAGENITAL LICHEN SCLEROSUS

Abstract:Lichen sclerosus is a chronic inflammatory disease of the skin and mucous membranes coated with squamous nonkeratinizing epithelium. The etiology of this disease is not completely clear. The exact prevalence of the disease is quite difficult to establish due to a lack of awareness of medica...

Full description

Saved in:
Bibliographic Details
Main Authors: O. O. Katz, F. A. Trifonov, V. V. Kuznetsov
Format: Article
Language:Russian
Published: QUASAR, LLC 2015-10-01
Series:Исследования и практика в медицине
Subjects:
Online Access:https://www.rpmj.ru/rpmj/article/view/83
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849241222280904704
author O. O. Katz
F. A. Trifonov
V. V. Kuznetsov
author_facet O. O. Katz
F. A. Trifonov
V. V. Kuznetsov
author_sort O. O. Katz
collection DOAJ
description Abstract:Lichen sclerosus is a chronic inflammatory disease of the skin and mucous membranes coated with squamous nonkeratinizing epithelium. The etiology of this disease is not completely clear. The exact prevalence of the disease is quite difficult to establish due to a lack of awareness of medical staff about the disease and relatively few patients visit medical specialists. Many researchers lean towards autoimmune theory of the origin of the disease. This is the basis for the most common methods of treatment. We have the information that lichen sclerosus may be caused by trauma, hormonal disorders and infectious lesions. In some cases genetic predisposition is observed. Standard treatment for lichen sclerosus is the topical application of glucocorticosteroids. If this treatment is ineffective topical calcineurin inhibitors are used. However, in many cases both treatments of lichen sclerosus are ineffective. In response to the problem alternative therapies can be used. Efficiency of phototherapy and photodynamic therapy for some cutaneous diseases is well known, in this regard it is important to examine in depth possibilities of these methods for treatment of lichen sclerosus.
format Article
id doaj-art-a1c561a1e132436f932b37b7ab5c3704
institution Kabale University
issn 2410-1893
language Russian
publishDate 2015-10-01
publisher QUASAR, LLC
record_format Article
series Исследования и практика в медицине
spelling doaj-art-a1c561a1e132436f932b37b7ab5c37042025-08-20T04:00:14ZrusQUASAR, LLCИсследования и практика в медицине2410-18932015-10-0123515810.17709/2409-2231-2015-2-3-51-5856PHOTOTHERAPY AND PHOTODYNAMIC THERAPY IN THE TREATMENT OF EXTRAGENITAL LICHEN SCLEROSUSO. O. Katz0F. A. Trifonov1V. V. Kuznetsov2INPE MEPhI (Obninsk, Russian Federation)INPE MEPhI (Obninsk, Russian Federation)INPE MEPhI (Obninsk, Russian Federation)Abstract:Lichen sclerosus is a chronic inflammatory disease of the skin and mucous membranes coated with squamous nonkeratinizing epithelium. The etiology of this disease is not completely clear. The exact prevalence of the disease is quite difficult to establish due to a lack of awareness of medical staff about the disease and relatively few patients visit medical specialists. Many researchers lean towards autoimmune theory of the origin of the disease. This is the basis for the most common methods of treatment. We have the information that lichen sclerosus may be caused by trauma, hormonal disorders and infectious lesions. In some cases genetic predisposition is observed. Standard treatment for lichen sclerosus is the topical application of glucocorticosteroids. If this treatment is ineffective topical calcineurin inhibitors are used. However, in many cases both treatments of lichen sclerosus are ineffective. In response to the problem alternative therapies can be used. Efficiency of phototherapy and photodynamic therapy for some cutaneous diseases is well known, in this regard it is important to examine in depth possibilities of these methods for treatment of lichen sclerosus.https://www.rpmj.ru/rpmj/article/view/83phototherapyphotodynamic therapylichen sclerosusskinmucous membranes
spellingShingle O. O. Katz
F. A. Trifonov
V. V. Kuznetsov
PHOTOTHERAPY AND PHOTODYNAMIC THERAPY IN THE TREATMENT OF EXTRAGENITAL LICHEN SCLEROSUS
Исследования и практика в медицине
phototherapy
photodynamic therapy
lichen sclerosus
skin
mucous membranes
title PHOTOTHERAPY AND PHOTODYNAMIC THERAPY IN THE TREATMENT OF EXTRAGENITAL LICHEN SCLEROSUS
title_full PHOTOTHERAPY AND PHOTODYNAMIC THERAPY IN THE TREATMENT OF EXTRAGENITAL LICHEN SCLEROSUS
title_fullStr PHOTOTHERAPY AND PHOTODYNAMIC THERAPY IN THE TREATMENT OF EXTRAGENITAL LICHEN SCLEROSUS
title_full_unstemmed PHOTOTHERAPY AND PHOTODYNAMIC THERAPY IN THE TREATMENT OF EXTRAGENITAL LICHEN SCLEROSUS
title_short PHOTOTHERAPY AND PHOTODYNAMIC THERAPY IN THE TREATMENT OF EXTRAGENITAL LICHEN SCLEROSUS
title_sort phototherapy and photodynamic therapy in the treatment of extragenital lichen sclerosus
topic phototherapy
photodynamic therapy
lichen sclerosus
skin
mucous membranes
url https://www.rpmj.ru/rpmj/article/view/83
work_keys_str_mv AT ookatz phototherapyandphotodynamictherapyinthetreatmentofextragenitallichensclerosus
AT fatrifonov phototherapyandphotodynamictherapyinthetreatmentofextragenitallichensclerosus
AT vvkuznetsov phototherapyandphotodynamictherapyinthetreatmentofextragenitallichensclerosus