New perspectives of the role of skeletal muscle derived extracellular vesicles in the pathogenesis of amyotrophic lateral sclerosis: the ‘dying back’ hypothesis

Abstract Amyotrophic lateral sclerosis (ALS), is a progressive neurodegenerative disease that affects nerve cells in the brain and the spinal cord, and is characterized by muscle weakness, paralysis and ultimately, respiratory failure. The exact causes of ALS are not understood, though it is believe...

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Bibliographic Details
Main Authors: Carolina Sbarigia, Sophie Rome, Luciana Dini, Stefano Tacconi
Format: Article
Language:English
Published: Wiley 2024-11-01
Series:Journal of Extracellular Biology
Subjects:
Online Access:https://doi.org/10.1002/jex2.70019
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