The role of miRNA genes participating in VHL-HIF1α in clear cell renal cell carcinoma

The role of miRNA genes participating in VHL-HIF1α in clear cell renal cell carcinoma

Introduction. Much attention in ccRCC development is paid to VHL-HIF1α pathway genes. Numerous genes involved in the pathogenesis of ccRCC are targets for miRNA. Alteration in the nature of interaction with miRNA binding site as a result of a single nucleotide substitution may promote change the exp...

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Main Authors: V. N. Pavlov, I. R. Gilyazova, A. A. Izmailov, E. A. Klimentova, I. R. Sultanov, M. A. Bermishev, Z. R. Akhmadeev, A. Kh. Nurgalieva, G. V. Ishbulatova, E. K. Khusnutdinova
Format: Article
Language:Russian
Published: Ministry of Health of Russian Federation, Rostov State Medical University, State Budget Educational Institute of Higher Professional Education 2019-02-01
Series:Вестник урологии
Subjects:
mirna
binding sites
clear cell renal cell carcinoma
markers
Online Access:https://www.urovest.ru/jour/article/view/234
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