Elevated serum growth differentiation factor 15 and decorin predict the fibrotic progression of metabolic dysfunction-associated steatotic liver disease

Elevated serum growth differentiation factor 15 and decorin predict the fibrotic progression of metabolic dysfunction-associated steatotic liver disease

Abstract Mitochondrial dysfunction with oxidative stress contributes to metabolic dysfunction-associated steatotic liver disease (MASLD) progression. We aimed to evaluate the fibrosis predictive efficacy of a novel non-invasive diagnostic panel using metabolic stress biomarkers. From a population-ba...

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Bibliographic Details
Main Authors: Jae Seung Chang, Jhii-Hyun Ahn, Moon Young Kim, Kyu-Sang Park
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Subjects:
Hepatic fibrosis
Mitochondrial stress
Serum biomarker
Growth differentiation factor-15
Decorin
Online Access:https://doi.org/10.1038/s41598-024-77719-6
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https://doi.org/10.1038/s41598-024-77719-6

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