Effects of estrogen and mechanical loading on cultured cells derived from mandibular condylar cartilage
Abstract Temporomandibular joint osteoarthritis (TMJ-OA) is a degenerative condition influenced by mechanical loading and hormonal factors, particularly estrogen. Despite its established role in TMJ pathophysiology, the mechanisms underlying the effects of estrogen on joint cartilage remain unclear,...
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| Main Authors: | Jin Tsuchida, Yuya Nakao, Koken Sato, Osamu Uehara, Itaru Mizoguchi, Yoshihiro Abiko, Masahiro Iijima |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
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| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-07770-4 |
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