A novel structural modeling magnitude and orientation radiomic descriptor for evaluating response to neoadjuvant therapy in rectal cancers via MRI

Abstract With advances in neoadjuvant therapies for rectal cancer, accurately evaluating tumor regression and response is increasingly critical for enabling personalized follow-up, including non-operative management. Given the lack of reliable assessment methods, there is an opportunity to develop c...

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Main Authors: Charlems Alvarez-Jimenez, Jacob T. Antunes, Thomas DeSilvio, Zhouping Wei, Marwa Ismail, Joseph E. Willis, Emily Steinhagen, Andrei Purysko, David Liska, Smitha Krishnamurthi, Marka Crittenden, Michael Gough, Kristina Young, Anant Madabhushi, Eduardo Romero, Pallavi Tiwari, Satish E. Viswanath
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-025-01007-3
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