Unveiling the NEFH+ malignant cell subtype: Insights from single-cell RNA sequencing in prostate cancer progression and tumor microenvironment interactions

Unveiling the NEFH+ malignant cell subtype: Insights from single-cell RNA sequencing in prostate cancer progression and tumor microenvironment interactions

BackgroundProstate cancer (PCa) is a multifactorial and heterogeneous disease, ranking among the most prevalent malignancies in men. In 2020, there were 1,414,259 new cases of PCa worldwide, accounting for 7.3% of all malignant tumors. The incidence rate of PCa ranks third, following breast cancer a...

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Bibliographic Details
Main Authors: Jie Wang, Fu Zhao, Qiang Zhang, Zhou Sun, Zhikai Xiahou, Changzhong Wang, Yan Liu, Zongze Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Immunology
Subjects:
multi-omics
single-cell RNA sequencing
prostate cancer
tumor heterogeneity
precision medicine
drug discovery
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1517679/full
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