Altered platelet lipidome in bleeding patients with unexplained platelet function defects

Altered platelet lipidome in bleeding patients with unexplained platelet function defects

In patients with a mild to moderate bleeding disorder (MBD) and abnormal light transmission aggregometry (LTA), a platelet function defect (PFD) is suspected. However, in many patients with PFD, the underlying mechanism remains elusive. Given the essential role of lipids in platelet signaling, plat...

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Main Authors: Bianca de Jonckheere, Dino Mehic, Dominik Kopczynski, Anita Pirabe, Waltraud Schrottmaier, Anna Schmuckenschlager, Cristina Coman, Tim Dreier, Helmuth Haslacher, Alexander Tolios, Cihan Ay, Ingrid Pabinger, Johanna Gebhart, Robert Ahrends, Alice Assinger
Format: Article
Language:English
Published: Ferrata Storti Foundation 2025-07-01
Series:Haematologica
Online Access:https://haematologica.org/article/view/12187
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https://haematologica.org/article/view/12187

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