Nanobody-mediated targeting of Plasmodium falciparum PfPIMMS43 can block malaria transmission in mosquitoes
Abstract The transition from ookinete to oocyst is a critical step in the Plasmodium falciparum lifecycle and an important target for malaria transmission-blocking strategies. PfPIMMS43, a surface protein of P. falciparum ookinetes and sporozoites, is critical for this transition and aids the parasi...
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| Main Authors: | Chiamaka Valerie Ukegbu, Mgeni Mohamed, Astrid Hoermann, Yuyan Qin, Prisca A. Kweyamba, Dickson Wilson Lwetoijera, Nikolai Windbichler, Sarah Moore, George K. Christophides, Dina Vlachou |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-04-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-025-08033-8 |
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