Engineering a newly identified alcohol dehydrogenase from Sphingobium Sp. for efficient utilization of nicotinamide cofactors biomimetics

Engineering a newly identified alcohol dehydrogenase from Sphingobium Sp. for efficient utilization of nicotinamide cofactors biomimetics

Abstract Nicotinamide cofactor biomimetics (NCBs) serve as low-cost alternatives to the expensive NAD(P)+/NAD(P)H, holding significant potential for applications in oxidoreductases. In this study, an alcohol dehydrogenase (SpADH2) from Sphingobium sp. SYK-6 was identified for the utilization of synt...

Full description

Saved in:
Bibliographic Details
Main Authors: Yichun Zhu, Jieyu Zhou, Xiangyuan Gu, Huiru Wang, Hao Han, Ye Ni
Format: Article
Language:English
Published: SpringerOpen 2025-05-01
Series:Bioresources and Bioprocessing
Subjects:
Alcohol dehydrogenase
Nicotinamide cofactor biomimetics (NCBs)
Syringyl alcohol
Semi-rational engineering
Cofactor specificity
Online Access:https://doi.org/10.1186/s40643-025-00870-z
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1186/s40643-025-00870-z

Similar Items