Effects of the estrous cycle and sex on stress responses in guinea pigs

Abstract Sex differences in hypothalamic-pituitary-adrenal (HPA)-axis functions and related stress responsiveness can strongly depend on influences of gonadal hormones and their fluctuations during the female estrous or menstrual cycle. Females usually show higher HPA-axis activity and glucocorticoi...

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Bibliographic Details
Main Authors: Matthias Nemeth, Selina M. Herrmann, Bernard Wallner, Eva Millesi
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-11101-y
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