Lactiplantibacillus plantarum attenuate gossypol-induced hepatic lipotoxicity by altering intestinal microbiota for enriching microbial tryptophan metabolites in Nile tilapia (Oreochromis niloticus)

Lactiplantibacillus plantarum attenuate gossypol-induced hepatic lipotoxicity by altering intestinal microbiota for enriching microbial tryptophan metabolites in Nile tilapia (Oreochromis niloticus)

Abstract Background Free fatty acids (FFAs) are the main cause of fatty liver disease, which can be alleviated by modulation of intestinal microbiota. Lactiplantibacillus plantarum plays a key role in maintaining liver health, but the underlying mechanism remains unclear. Results Here, a strain affi...

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Bibliographic Details
Main Authors: Fei-Fei Ding, Nan-Nan Zhou, Yue-Jian Mao, Jing Yang, Samwel M. Limbu, Jorge Galindo-Villegas, Zhen-Yu Du, Mei-Ling Zhang
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Microbiome
Subjects:
Lactiplantibacillus plantarum
Free fatty acids
Lipotoxicity
Gut microbiota
Microbial tryptophan metabolites
Online Access:https://doi.org/10.1186/s40168-025-02172-0
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https://doi.org/10.1186/s40168-025-02172-0

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