Staphylococcus aureus enterotoxin sensitization is associated with declined capsaicin cough sensitivity in chronic obstructive pulmonary disease

Staphylococcus aureus enterotoxin sensitization is associated with declined capsaicin cough sensitivity in chronic obstructive pulmonary disease

Abstract Sensitization to Staphylococcus aureus (S. aureus) enterotoxins (SEs) A (SEA) and B (SEB) is associated with the pathogenesis of several chronic airway diseases, including asthma and chronic rhinosinusitis, but its role in chronic obstructive pulmonary disease (COPD) remains unclear. This c...

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Main Authors: Yoshihiro Kanemitsu, Kensuke Fukumitsu, Ryota Kurokawa, Taisuke Akamatsu, Satoshi Fukuda, Yutaka Ito, Yuki Amakusa, Tatsuro Suzuki, Keima Ito, Yuta Mori, Takehiro Uemura, Tomoko Tajiri, Hirotsugu Ohkubo, Toshihiro Shirai, Akio Niimi
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Subjects:
Capsaicin cough reflex sensitivity
Chronic obstructive pulmonary disease
Staphylococcus aureus
Staphylococcus aureus enterotoxins
IgE
Online Access:https://doi.org/10.1038/s41598-024-81297-y
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https://doi.org/10.1038/s41598-024-81297-y

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