Structural modeling of phosphatidylinositol 3-kinase-γ with novel derivatives of stilbenoids

Phosphatidylinositol 3-kinases (PI3K) form a family of lipid kinases that catalyze the phosphorylation of 3-hydroxyl group of the inositol ring of phosphatidylinositol and its derivatives. It is implicated in inflammatory disorders and cancer thus making it an attractive drug target. Crystal structu...

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Bibliographic Details
Main Authors: Sagar Rathee, Madhan Vishal Rajan, Simran Sharma, Gururao Hariprasad
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Biochemistry and Biophysics Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2405580824002255
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