TSC2-mutated perivascular epithelioid cell tumor with partial response to mTOR inhibition: a case report and literature review

TSC2-mutated perivascular epithelioid cell tumor with partial response to mTOR inhibition: a case report and literature review

Abstract Perivascular epithelioid cell tumors (PEComas), rare mesenchymal neoplasms with heterogeneous behavior, are molecularly characterized by TSC2 inactivation driving mammalian target of rapamycin (mTOR) pathway activation. We present a typical case of a 63-year-old female with metastatic high-...

Full description

Saved in:
Bibliographic Details
Main Authors: Xiaopeng Suo, Ruihan Dong, Lingling Zhang, Xiaoying Zhang, Xiangji Li, Mengmeng Xiao
Format: Article
Language:English
Published: Springer 2025-07-01
Series:Discover Oncology
Subjects:
PEComa
mTOR inhibitor
Everolimus
TSC2 mutation
Case report
Online Access:https://doi.org/10.1007/s12672-025-03270-z
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1007/s12672-025-03270-z

Similar Items