Metformin in Antiviral Therapy: Evidence and Perspectives

Metformin in Antiviral Therapy: Evidence and Perspectives

Metformin, a widely used antidiabetic medication, has emerged as a promising broad-spectrum antiviral agent due to its ability to modulate cellular pathways essential for viral replication. By activating AMPK, metformin depletes cellular energy reserves that viruses rely on, effectively limiting the...

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Bibliographic Details
Main Authors: Iryna Halabitska, Pavlo Petakh, Oleh Lushchak, Iryna Kamyshna, Valentyn Oksenych, Oleksandr Kamyshnyi
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Viruses
Subjects:
metformin
broad-spectrum antiviral
AMPK activation
mTOR inhibition
viral replication
oxidative stress
Online Access:https://www.mdpi.com/1999-4915/16/12/1938
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