Landscape of the Peripheral Immune Response Induced by Intraoperative Radiotherapy Combined with Surgery in Early Breast Cancer Patients

Landscape of the Peripheral Immune Response Induced by Intraoperative Radiotherapy Combined with Surgery in Early Breast Cancer Patients

Abstract A comprehensive analysis of the immune response triggered by intraoperative radiation therapy (IORT) remains incomplete. In this study, single‐cell RNA sequencing and single‐cell T cell receptor sequencing are conducted on peripheral blood mononuclear cells (PBMCs) from patient with early‐s...

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Bibliographic Details
Main Authors: Danian Dai, Xuerui Li, Hongkai Zhuang, Yun Ling, Lezi Chen, Cheng Long, Jinhui Zhang, Yunjie Wang, Yuehua Li, Hailin Tang, Bo Chen
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Advanced Science
Subjects:
breast cancer
intraoperative radiotherapy
peripheral immune response
single‐cell RNA sequencing
single‐cell T cell receptor sequencing
Online Access:https://doi.org/10.1002/advs.202308174
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