The cGAS-STING pathway drives neuroinflammation and neurodegeneration via cellular and molecular mechanisms in neurodegenerative diseases

The cGAS-STING pathway drives neuroinflammation and neurodegeneration via cellular and molecular mechanisms in neurodegenerative diseases

Neurodegenerative diseases (NDs) are a type of common chronic progressive disorders characterized by progressive damage to specific cell populations in the nervous system, ultimately leading to disability or death. Effective treatments for these diseases are still lacking, due to a limited understan...

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Bibliographic Details
Main Authors: Yuxin Zhang, Meijuan Zou, Hao Wu, Jie Zhu, Tao Jin
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:Neurobiology of Disease
Subjects:
cGAS-STING
Microglia
Astrocyte
Neuron
Innate immune system
Adaptive immune system
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996124003115
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