PREVALENCE, TOXICOKINETICS AND CLINICAL SIGNS OF ZEARALENONE MYCOTOXICOSIS IN PIGS - AN OVERVIEW

The contamination of feeds and foods with mycotoxins is a global ecological and public health issue. The effects of fungi growing on feeds and of mycotoxins produced by them are outlined with the fact that even minimum concentrations, especially in cases of potentiated synergism and continuous ex...

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Main Authors: N. Nikolov, R. Binev
Format: Article
Language:English
Published: Trakia University 2023-09-01
Series:Trakia Journal of Sciences
Subjects:
Online Access:http://tru.uni-sz.bg/tsj/Volume%2021,%202023,%20Number%203,%20Series%20Biomedical%20Sciences/9_N.Nikolov.pdf
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author N. Nikolov
R. Binev
author_facet N. Nikolov
R. Binev
author_sort N. Nikolov
collection DOAJ
description The contamination of feeds and foods with mycotoxins is a global ecological and public health issue. The effects of fungi growing on feeds and of mycotoxins produced by them are outlined with the fact that even minimum concentrations, especially in cases of potentiated synergism and continuous exposure, may cause substantial harm to health manifested with immunosuppression, reproductive disorders in farm animals and hence, reduced productive performance and great economic losses. By affecting numerous economic sectors and the food industry in particular, mycotoxins pose a huge threat to animal and human health. The Food and Agriculture Organization (FAO) reports that 25% of global food crops used as primary feed ingredients in animal and human nutrition are affected by mycotoxins and contaminated as early as during the stages of plant growth, harvesting, transportation or storage. The most important mycotoxins, subject to extensive research and of enormous economic relevance in modern livestock husbandry, pig farming in particular, are deoxynivalenol (DON), zearalenone (ZEA), T-2 toxin (T-2), fumonisin B1 (FB1), ochratoxin A (OTA) and aflatoxin B1 (AFB1). The present review describes zearalenone (ZEA) as one of the main pig feed contaminants, its prevalence, toxicokinetics, toxicodynamics and clinical signs.
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spelling doaj-art-9fa14aa4aa1f4f6a9f8fe1ab71a0f9082025-08-20T03:44:32ZengTrakia UniversityTrakia Journal of Sciences1313-35512023-09-0121327928510.15547/tjs.2023.03.009PREVALENCE, TOXICOKINETICS AND CLINICAL SIGNS OF ZEARALENONE MYCOTOXICOSIS IN PIGS - AN OVERVIEWN. NikolovR. BinevThe contamination of feeds and foods with mycotoxins is a global ecological and public health issue. The effects of fungi growing on feeds and of mycotoxins produced by them are outlined with the fact that even minimum concentrations, especially in cases of potentiated synergism and continuous exposure, may cause substantial harm to health manifested with immunosuppression, reproductive disorders in farm animals and hence, reduced productive performance and great economic losses. By affecting numerous economic sectors and the food industry in particular, mycotoxins pose a huge threat to animal and human health. The Food and Agriculture Organization (FAO) reports that 25% of global food crops used as primary feed ingredients in animal and human nutrition are affected by mycotoxins and contaminated as early as during the stages of plant growth, harvesting, transportation or storage. The most important mycotoxins, subject to extensive research and of enormous economic relevance in modern livestock husbandry, pig farming in particular, are deoxynivalenol (DON), zearalenone (ZEA), T-2 toxin (T-2), fumonisin B1 (FB1), ochratoxin A (OTA) and aflatoxin B1 (AFB1). The present review describes zearalenone (ZEA) as one of the main pig feed contaminants, its prevalence, toxicokinetics, toxicodynamics and clinical signs.http://tru.uni-sz.bg/tsj/Volume%2021,%202023,%20Number%203,%20Series%20Biomedical%20Sciences/9_N.Nikolov.pdfzearalenone (zea)prevalencetoxicitymetabolismpigs
spellingShingle N. Nikolov
R. Binev
PREVALENCE, TOXICOKINETICS AND CLINICAL SIGNS OF ZEARALENONE MYCOTOXICOSIS IN PIGS - AN OVERVIEW
Trakia Journal of Sciences
zearalenone (zea)
prevalence
toxicity
metabolism
pigs
title PREVALENCE, TOXICOKINETICS AND CLINICAL SIGNS OF ZEARALENONE MYCOTOXICOSIS IN PIGS - AN OVERVIEW
title_full PREVALENCE, TOXICOKINETICS AND CLINICAL SIGNS OF ZEARALENONE MYCOTOXICOSIS IN PIGS - AN OVERVIEW
title_fullStr PREVALENCE, TOXICOKINETICS AND CLINICAL SIGNS OF ZEARALENONE MYCOTOXICOSIS IN PIGS - AN OVERVIEW
title_full_unstemmed PREVALENCE, TOXICOKINETICS AND CLINICAL SIGNS OF ZEARALENONE MYCOTOXICOSIS IN PIGS - AN OVERVIEW
title_short PREVALENCE, TOXICOKINETICS AND CLINICAL SIGNS OF ZEARALENONE MYCOTOXICOSIS IN PIGS - AN OVERVIEW
title_sort prevalence toxicokinetics and clinical signs of zearalenone mycotoxicosis in pigs an overview
topic zearalenone (zea)
prevalence
toxicity
metabolism
pigs
url http://tru.uni-sz.bg/tsj/Volume%2021,%202023,%20Number%203,%20Series%20Biomedical%20Sciences/9_N.Nikolov.pdf
work_keys_str_mv AT nnikolov prevalencetoxicokineticsandclinicalsignsofzearalenonemycotoxicosisinpigsanoverview
AT rbinev prevalencetoxicokineticsandclinicalsignsofzearalenonemycotoxicosisinpigsanoverview