Polyunsaturated fatty-acids diet increases fear discrimination in rats and IGF-2 receptors signaling in the auditory cortex

Abstract Recent studies suggest that diet influences brain functions, though its effects on emotional processes remain unclear. Here we explored how two high-fat diets affect innate and learned fear behaviors in rats. One group was fed a polyunsaturated fatty acids-enriched diet, another received a...

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Bibliographic Details
Main Authors: Giulia Concina, Eugenio Manassero, Felice Cicciarelli, Annamaria Renna, Luisella Milano, Federica Scarpina, Alessandro Mauro, Benedetto Sacchetti
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-01900-8
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