The distribution of Hypocretin/Orexin receptor mRNA in the mouse and human brain

The distribution of Hypocretin/Orexin receptor mRNA in the mouse and human brain

Hypocretin (Hcrtr, HCRTR) / orexin (OX) receptors modulate a range of neurobiological functions and are drug targets for several disorders. Mapping the distribution of receptors in the brain can inform their function and guide targeting of specific disorders. Although studied in rodents, orexin rece...

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Bibliographic Details
Main Authors: Sanjida Mir, Ryan J. Keenan, Romke Bron, Cameron J. Nowell, Catriona McLean, Leah C. Beauchamp, Laura J. Vella, Brian Dean, Daniel Hoyer, Laura H. Jacobson
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Medicine in Drug Discovery
Subjects:
Hypocretin
Orexin
hypocretin receptor mRNA
Orexin receptors
In situ hybridization
Online Access:http://www.sciencedirect.com/science/article/pii/S2590098624000277
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