The Frequency, Severity, and Risk Factors of Hickman CatheterRelated Complications in Pediatric Cancer Patients: A Single-Center Experience from Bosnia and Herzegovina
Objective: This study aimed to identify the frequency, severity, and risk factors associated with Hickman catheter-related complications in children with hemato-oncological malignancies at the largest pediatric tertiary care unit in Bosnia and Herzegovina. Materials and Methods: A cross-sectional...
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| Format: | Article |
| Language: | English |
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AVES Yayincilik
2024-03-01
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| Series: | Turkish Archives of Pediatrics |
| Online Access: | https://turkarchpediatr.org/en/the-frequency-severity-and-risk-factors-of-hickman-catheterrelated-complications-in-pediatric-cancer-patients-a-single-center-experience-from-bosnia-and-herzegovina-131638 |
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| author | Zlatan Zvizdic Emin Zaimovic Emir Milisic Asmir Jonuzi Una Glamoclija Semir Vranic |
| author_facet | Zlatan Zvizdic Emin Zaimovic Emir Milisic Asmir Jonuzi Una Glamoclija Semir Vranic |
| author_sort | Zlatan Zvizdic |
| collection | DOAJ |
| description | Objective: This study aimed to identify the frequency, severity, and risk factors associated with Hickman catheter-related complications in children with hemato-oncological malignancies at the largest pediatric tertiary care unit in Bosnia and Herzegovina.
Materials and Methods: A cross-sectional study was conducted on a cohort of pediatric cancer patients who underwent Hickman central venous catheters (CVCs) between January 2019 and December 2022. Mechanical, infectious, and thrombotic Hickman catheter-related complications were evaluated and analyzed. We also investigated possible risk factors associated with these complications.
Results: Seventy-one Hickman CVCs were inserted in 68 children (44 boys and 24 girls) at a mean age of 6.9 ± 4.6. Forty (58.8%) children had hematological malignancies and 28 (41.2%) solid cancers. The median follow-up after Hickman CVC insertion was 190 days (95% CI [160-212]) for 12 644 catheter days. During follow-up, 10 (14.1%) mechanical, 7 (9.9%) infectious, and 1 (1.4%) thrombotic complications were recorded (0.8, 0.48, and 0.08 for mechanical, infectious, and thrombotic complications per 1000 catheter days, respectively). A slightly higher incidence of complications was recorded in children with hematological malignancies (1.59 per 1000 catheter days) compared with children with solid cancers (1.22 complications per 1000 catheter days).
Conclusion: Using Hickman CVCs for long-term venous access in infusional chemotherapy for pediatric cancer patients is safe but is associated with significant morbidity. |
| format | Article |
| id | doaj-art-9f2328df5f0a41be8ab3d9b49b481b5e |
| institution | Kabale University |
| issn | 2757-6256 |
| language | English |
| publishDate | 2024-03-01 |
| publisher | AVES Yayincilik |
| record_format | Article |
| series | Turkish Archives of Pediatrics |
| spelling | doaj-art-9f2328df5f0a41be8ab3d9b49b481b5e2024-11-26T14:38:41ZengAVES YayincilikTurkish Archives of Pediatrics2757-62562024-03-0159214414910.5152/TurkArchPediatr.2024.23179The Frequency, Severity, and Risk Factors of Hickman CatheterRelated Complications in Pediatric Cancer Patients: A Single-Center Experience from Bosnia and HerzegovinaZlatan Zvizdic0Emin Zaimovic1Emir Milisic2Asmir Jonuzi3Una Glamoclija4Semir Vranic5Department of Pediatric Surgery, Clinical Center University of Sarajevo, Sarajevo, Bosnia and HerzegovinaUniversity of Sarajevo Faculty of Medicine, Sarajevo, Bosnia and Herzegovina ; Public Health Center Breza, Breza, Bosnia and HerzegovinaDepartment of Pediatric Surgery, Clinical Center University of Sarajevo, Sarajevo, Bosnia and HerzegovinaDepartment of Pediatric Surgery, Clinical Center University of Sarajevo, Sarajevo, Bosnia and HerzegovinaScientific Research Unit, Bosnalijek d.d., Sarajevo, Bosnia and Herzegovina ; Department of Biochemistry and Clinical Analysis, University of Sarajevo Faculty of Pharmacy, Sarajevo, Bosnia and HerzegovinaQU Health, Qatar University College of Medicine, Doha, QatarObjective: This study aimed to identify the frequency, severity, and risk factors associated with Hickman catheter-related complications in children with hemato-oncological malignancies at the largest pediatric tertiary care unit in Bosnia and Herzegovina. Materials and Methods: A cross-sectional study was conducted on a cohort of pediatric cancer patients who underwent Hickman central venous catheters (CVCs) between January 2019 and December 2022. Mechanical, infectious, and thrombotic Hickman catheter-related complications were evaluated and analyzed. We also investigated possible risk factors associated with these complications. Results: Seventy-one Hickman CVCs were inserted in 68 children (44 boys and 24 girls) at a mean age of 6.9 ± 4.6. Forty (58.8%) children had hematological malignancies and 28 (41.2%) solid cancers. The median follow-up after Hickman CVC insertion was 190 days (95% CI [160-212]) for 12 644 catheter days. During follow-up, 10 (14.1%) mechanical, 7 (9.9%) infectious, and 1 (1.4%) thrombotic complications were recorded (0.8, 0.48, and 0.08 for mechanical, infectious, and thrombotic complications per 1000 catheter days, respectively). A slightly higher incidence of complications was recorded in children with hematological malignancies (1.59 per 1000 catheter days) compared with children with solid cancers (1.22 complications per 1000 catheter days). Conclusion: Using Hickman CVCs for long-term venous access in infusional chemotherapy for pediatric cancer patients is safe but is associated with significant morbidity.https://turkarchpediatr.org/en/the-frequency-severity-and-risk-factors-of-hickman-catheterrelated-complications-in-pediatric-cancer-patients-a-single-center-experience-from-bosnia-and-herzegovina-131638 |
| spellingShingle | Zlatan Zvizdic Emin Zaimovic Emir Milisic Asmir Jonuzi Una Glamoclija Semir Vranic The Frequency, Severity, and Risk Factors of Hickman CatheterRelated Complications in Pediatric Cancer Patients: A Single-Center Experience from Bosnia and Herzegovina Turkish Archives of Pediatrics |
| title | The Frequency, Severity, and Risk Factors of Hickman CatheterRelated Complications in Pediatric Cancer Patients: A Single-Center Experience from Bosnia and Herzegovina |
| title_full | The Frequency, Severity, and Risk Factors of Hickman CatheterRelated Complications in Pediatric Cancer Patients: A Single-Center Experience from Bosnia and Herzegovina |
| title_fullStr | The Frequency, Severity, and Risk Factors of Hickman CatheterRelated Complications in Pediatric Cancer Patients: A Single-Center Experience from Bosnia and Herzegovina |
| title_full_unstemmed | The Frequency, Severity, and Risk Factors of Hickman CatheterRelated Complications in Pediatric Cancer Patients: A Single-Center Experience from Bosnia and Herzegovina |
| title_short | The Frequency, Severity, and Risk Factors of Hickman CatheterRelated Complications in Pediatric Cancer Patients: A Single-Center Experience from Bosnia and Herzegovina |
| title_sort | frequency severity and risk factors of hickman catheterrelated complications in pediatric cancer patients a single center experience from bosnia and herzegovina |
| url | https://turkarchpediatr.org/en/the-frequency-severity-and-risk-factors-of-hickman-catheterrelated-complications-in-pediatric-cancer-patients-a-single-center-experience-from-bosnia-and-herzegovina-131638 |
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