Curcumin's Protective Role in Heatstroke‐Induced Acute Liver Injury: Targeting Pyroptosis and Enhancing SIRT1 Expression

Abstract Heatstroke (HS) is a severe systemic condition that significantly impacts organ function, with the liver being particularly vulnerable. Sirtuin 1 (SIRT1), a crucial deacetylase, is implicated in various diseases' pathophysiology. Curcumin, a natural polyphenol, has been shown to modula...

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Bibliographic Details
Main Authors: Yizhan Wu, Fei Guo, Yan Ma, Weihao Chai, Jiajia Li, Wenhui Shi, Jiangwei Liu
Format: Article
Language:English
Published: Wiley 2024-12-01
Series:Global Challenges
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Online Access:https://doi.org/10.1002/gch2.202400178
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