ANGPTL4 exacerbates pancreatitis by augmenting acinar cell injury through upregulation of C5a

ANGPTL4 exacerbates pancreatitis by augmenting acinar cell injury through upregulation of C5a

Abstract Pancreatitis is the inflammation of the pancreas. However, little is known about the genes associated with pancreatitis severity. Our microarray analysis of pancreatic tissues from mild and severe acute pancreatitis mice models identified angiopoietin‐like 4 (ANGPTL4) as one of the most sig...

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Main Authors: Kyung Hee Jung, Mi Kwon Son, Hong Hua Yan, Zhenghuan Fang, Juyoung Kim, Soo Jung Kim, Jung Hee Park, Ji Eun Lee, Young‐Chan Yoon, Myeong Seong Seo, Beom Seok Han, Soyeon Ko, Young Ju Suh, Joo Han Lim, Don‐Haeng Lee, Ziqiang Teo, Jonathan Wei Kiat Wee, Nguan Soon Tan, Soon‐Sun Hong
Format: Article
Language:English
Published: Springer Nature 2020-07-01
Series:EMBO Molecular Medicine
Subjects:
acute pancreatitis
ANGPTL4
C5a
macrophage
Online Access:https://doi.org/10.15252/emmm.201911222
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https://doi.org/10.15252/emmm.201911222

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