Evaluation of PCV2 vaccine immunogenicity and efficacy using ELISpot to detect virus-specific memory B cells

Evaluation of PCV2 vaccine immunogenicity and efficacy using ELISpot to detect virus-specific memory B cells

Abstract Background Porcine Circovirus 2 (PCV2) vaccination plays a crucial role in preventing porcine circovirus-associated disease (PCVAD). Nevertheless, pig farms face significant challenges in evaluating vaccination efficacy due to the inability of PCV2 vaccines to achieve sterilizing immunity a...

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Main Authors: Jie Fan, Fangcheng Fan, Zhixiong Chen, Ping Chen, Yanli Zhu, Xin Li, Tiantian Liu, Runcheng Li, Wei Dong, Meng Ge
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Porcine Health Management
Subjects:
Porcine circovirus 2
ELISpot
Memory B cells
Immune memory
Vaccine
Online Access:https://doi.org/10.1186/s40813-025-00452-7
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https://doi.org/10.1186/s40813-025-00452-7

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