Targeting Zfp36 to combat cardiac hypertrophy: Insights into ferroptosis pathways

Targeting Zfp36 to combat cardiac hypertrophy: Insights into ferroptosis pathways

Abstract Background Cardiac hypertrophy is a precursor to heart failure and represents a significant global cause of mortality, thereby necessitating timely and effective therapeutic interventions. Zinc finger protein 36 (Zfp36) is recognised as a critical regulator of ferroptosis; however, its role...

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Main Authors: Mingyu Zhang, Xiaoxiang Guan, Zheng Dong, Chenxu Yang, Chao Xiong, Wenzheng Cheng, Aijing Shang, Yaru Liu, Xiaofei Guo, Bowen Zhang, Bo Zhang, Saidi Jin, Wenyi Qi, Berezhnova Tatjana Alexandrovna, Yuan Jiang, Zhimin Du, Chaoqian Xu
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:Clinical and Translational Medicine
Subjects:
cardiac hypertrophy
ferroptosis
RNA binding
Ythdc2
Zfp36
Online Access:https://doi.org/10.1002/ctm2.70247
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https://doi.org/10.1002/ctm2.70247

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