Bioinformatic screen with clinical validation for the identification of novel stool based mRNA biomarkers for the detection of colorectal lesions including advanced adenoma

Bioinformatic screen with clinical validation for the identification of novel stool based mRNA biomarkers for the detection of colorectal lesions including advanced adenoma

Abstract Messenger RNA (mRNA) stool based biomarkers represent a promising approach for the diagnosis of colorectal cancer (CRC) and advanced adenoma (AA). But it is unclear which mRNA biomarkers have the most clinical utility. This study aims to partially fill this gap by performing an analysis whi...

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Bibliographic Details
Main Authors: Houcong Liu, Loren Hansen, Changpu Song, Haijiu Lin, Dan Chen, Zhufang Chen, Hekai Zhou, Xiao Yang, Wenying Pan, Jihui Du
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
mRNA biomarkers
Stool
Colorectal cancer
Diagnostics
Online Access:https://doi.org/10.1038/s41598-025-13074-4
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https://doi.org/10.1038/s41598-025-13074-4

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