Functional immune profiling of hyper- and hypo-inflammatory subphenotypes of critical illness: a secondary analysis

IntroductionRecent studies of adult sepsis patients demonstrate the existence of two subphenotypes that differ in risk of mortality: a hyper-inflammatory subphenotype with a high risk of mortality, and a hypo-inflammatory or “not hyper-inflamed” subphenotype with a relatively lower risk of mortality...

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Bibliographic Details
Main Authors: E. Scott Halstead, Daniel J. McKeone, Abigail M. Samuelsen, Shouhao Zhou, Anthony S. Bonavia
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1520848/full
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