Methylated SEPTIN9 plasma test for colorectal cancer detection may be applicable to Lynch syndrome

Methylated SEPTIN9 plasma test for colorectal cancer detection may be applicable to Lynch syndrome

Objective The plasma-based methylated SEPTIN9 (mSEPT9) is a colorectal cancer (CRC) screening test for adults aged 50–75 years who are at average risk for CRC and have refused colonoscopy or faecal-based screening tests. The applicability of mSEPT9 for high-risk persons with Lynch syndrome (LS), the...

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Main Authors: Maria Christensen, Andrew E Hendifar, Rachel Pearlman, Sigurdis Haraldsdottir, Albert de la Chapelle, Heather Hampel, Megan P Hitchins, Ingrid P Vogelaar, Kevin Brennan, Nianmin Zhou, Brock Martin, Rocio Alvarez, Xiaopu Yuan, Sungjin Kim, Maha Guindi, Matthew F Kalady, Jennifer DeVecchio, James M Church, Carrie Snyder, Stephen J Lanspa, Robert W Haile, Henry T Lynch
Format: Article
Language:English
Published: BMJ Publishing Group 2019-08-01
Series:BMJ Open Gastroenterology
Online Access:https://bmjopengastro.bmj.com/content/6/1/e000299.full
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https://bmjopengastro.bmj.com/content/6/1/e000299.full

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